Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: a narrative overview
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چکیده
منابع مشابه
Options to Expand HIV Viral Load Testing in South Africa: Evaluation of the GeneXpert® HIV-1 Viral Load Assay
BACKGROUND Expansion of HIV viral load (VL) testing services are required to meet increased targets for monitoring patients on antiretroviral treatment. South Africa currently tests >4million VLs per annum in 16 highly centralised, automated high-throughput laboratories. The Xpert HIV-1 VL assay (Cepheid) was evaluated against in-country predicates, the Roche Cobas Taqmanv2 and Abbott HIV-1RT, ...
متن کاملChallenges to pediatric HIV care and treatment in South Africa.
It is estimated that almost 300,000 children in South Africa have human immunodeficiency virus (HIV) infection. The disease is responsible for reversing decreases in child mortality. Few data exist evaluating the outcomes of the prevention of mother-to-child transmission of HIV (PMTCT) program, although PMTCT coverage appears to be low. Hospitals are still witnessing large numbers of admissions...
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Objective. To define the long-term (2-4 years) clinical and virological outcome of an antiretroviral treatment (ART) programme in rural South Africa. Methods. We performed a retrospective observational cohort study, including 735 patients who initiated ART. Biannual monitoring, including HIV-RNA testing, was performed. Primary endpoint was patient retention; virological suppression (HIV-RNA < 5...
متن کاملSustained viral suppression in HIV-infected patients receiving antiretroviral therapy.
The article, however, made a subtle but important mistake in characterizing the guidelines from the Department of Justice and the Federal Trade Commission published as a companion to the Medicare Shared Savings Program. The authors twice identify a “balance” between market power and integration efficiencies as the goal of the antitrust guidelines. The concept of balance misstates the vital role...
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ژورنال
عنوان ژورنال: AIDS Research and Therapy
سال: 2021
ISSN: 1742-6405
DOI: 10.1186/s12981-020-00324-w